Abstrato

An efficient regioselective bromination of activated aromatic compounds using 1,4-bis (triphenylphosphonium) butane peroxodisulfate

Mehdi Forouzani, Hassan Ghasemnejad-Bosra, Mahboobeh Khajavi, Mahmood Tajbakhsh

A mild, efûcient and highly chemo- and regioselective method for the bromination of electron rich aromatic molecules has been developed by electrophilic substitution of Br+, which was generated in situ from Br2 or KBr using 1,4-bis (triphenylphosphonium) butane peroxodisulfate (BTPPBPDS) as the oxidant. Free aromatic amines remained unaffected under the reaction conditions.