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Antidermatophytic Effects Of Crude Leaf Extracts Of Alseodaphne Andersonii

Versha Parcha, Atul Kaushik, Jeevan J.Kaushik, M.S.M.Rawat

Leaf extracts of Alseodaphne andersonii extracted with petroleum ether, chloroform, acetone and methanol were screened for antidermatophytic activity against various pathogenic fungi namely Epidermophyton floccosum var nigricans, Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Sporothrix schenckii and Aspergillus fumigatus. Acetone extract showed moderate antidermatophytic activity against tested organisms as reflected by the zone of inhibition, while methanolic extract showed a significant control of growth of Sporothrix schenckii, Trichophyton rubrum and Epidermophyton floccosum var nigricans. Minimam inhibitory concentration (MIC) and minimam fungicidal concentration (MFC) of methanolic extract were determined against Sporothrix schenckii and Trichophyton rubrum only. On the basis of above results we can conclude that leaf extracts of Alseodaphne andersonii is potentially active against dermatophytes.