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Antidiabetic effect of the leaves of Kandelia candel Linn

Vijai Lakshmi, Rajesh Kumar, Arvind Kumar Srivastava

The crude ethanolic extract of the leaves of the Kandelia candel (L.) showed promising antihypergycemic activity at a dose of 500 mg/kg dose in rats using SLM(35% lowering of blood sugar)and STZ model (20.5 % lowering of blood sugar). On further fractionation of ethanol extract the activity was found to be concentrated only in aqueous fraction (38% lowering of blood sugar in SLMmodel and 22%lowering of blood sugar in STZmodels at 250 mg/kg. dose).