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Anti-hepatotoxic activity of phyllanthus debelis

Amita Verma, Bahar Ahmed

In the present study, we evaluated the antihepatotoxic activity of the different fractions of Phyllanthus debelis by performing biochemical parameters and histopathological studies against toxicity caused by the carbon tetrachloride. The histopathological studies of the liver showed swelling and necrosis in hepatocytes in CCl4 treated rats, treatment with different fractions have reduced significantly the necrosis and swelling of the hepatocytes. The biochemical parameters also showed the significant antihepatotoxic activity.