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Anti-inflammatory and analgesic activity of Capparis zeylanica Linn.

Mishra Manas Ranjan, Mishra Ashutosh, Pradhan Dusmanta Kumar, Pradhan Amiya Ranjan, Panda Ashok Kumar, Behera Rajani Kanta, Jha Shivesh

The present workwas undertaken to explore the analgesic and anti-inflammatory activity of Capparis zeylanica Linn. (Capparidaceae) methanolic extract ofwhole plant.Analgesic activitywas performed by using hot plate and tail immersionmethods.Anti-inflammatory effectwas analyzed by carrageenan induced pawedema method.Adose of 250 mg/kg and 500mg/kg C. zeylanica methanolic extract showed significantAnalgesic effects {(Hot plate, 7.571.17), (Tail immersion, 5.550.66)} and {(Hot plate, 7.971.33), (Tail immersion, 6.501.17)} respectively.Anti-inflammatory effect of 500 mg/kgmethanolic extract showed higher percentage of inhibition (21.42%) at 180 min in comparison to 250 mg/kg (18.5%) followed by standard Diclofenac sodium(22.28%).