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Biotransformation of asiaticoside and asiatic acid by Nocardia sp NRRL-5646

Xiao-Yun Zhang, Ye-Wang Zhang

Asiaticoside and asiatic acid are important active components of Centella asiatica. Transformation of asiaticoside and asiatic acid by Nocardia sp NRRL -5646were investigated. The results indicated that asiaticoside could be removed glycoside and transformed to asatic acid or its isomer-arjulonic acid and asiatic acid sulfate byNocardia spNRRL-5646. The transformation results of asiatic acid byNocardia sp NRRL -5646 showed that asiatic acid could be converted to asiatic acid sulfate.