Abstrato

In- vitro anthelmintic activity of Trigonella foenum-graecum leaves and seeds (Fabaceae)

R.D.Bhalke, S.J.Anarthe, K.D.Sasane, S.N.Satpute, S.N.Shinde, V.S.Sangle

Present study reports anthelmintic activity of petroleum ether, chloroform, ethyl acetate and methanolic extracts obtained from the leaves and seeds of Trigonella foenum-graecum Linn. (Fabaceae) on Indian adult earthworms Pheretima posthuma. Phytochemical investigation shows the presence of sterol, terpenes, flavonoids, tannins and alkaloids. Amongst all extracts, ethyl acetate extract of leaves showed potent anthelmintic activity as compared with other extracts and the reference drug albendazole. Results show that anthelmintic activity is dose dependant.