Abstrato

Protective effects of polygonum multiflorum polysaccharide against H2O2-induced apoptosis in PC12 cells

Yatao Xu, Xiuhong Jiang, Shumei Wang, Shengwang Liang


Objective To investigate the protective effects of Polygonum Multiflorum polysaccharide (PMP) on H2O2-induced apoptosis in PC12 cells. Methods MTT assay was used to assess the viability of PC12 cells which exposed to PMP with gradient concentrations; Flow cytometry(FCM) assay was used to analyze the apoptosis ratio of PC12 cells; Hoechst 33258 stain assay was used to observe the changes in PC12 cells nuclear morphology; Results PMP could protect the PC12 cells morphology, reduce the apoptosis rate and rescue H2O2-induced changes in nuclear morphology. Conclusion These results indicated that PMP could protect PC12 cells from H2O2-induced damage.


Isenção de responsabilidade: Este resumo foi traduzido usando ferramentas de inteligência artificial e ainda não foi revisado ou verificado

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  • CASS
  • Google Scholar
  • Abra o portão J
  • Infraestrutura Nacional de Conhecimento da China (CNKI)
  • CiteFactor
  • Cosmos SE
  • Diretório de indexação de periódicos de pesquisa (DRJI)
  • Laboratórios secretos de mecanismos de pesquisa
  • Euro Pub
  • ICMJE

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