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Synthesis of β-Amino Carbonyl Compounds and 5-Unsubstituted 3, 4-Dihydropyrimidinones using Solid Supported Co(ClO4)2 Under Solvent Free Condition

Vishvanath D. Patil, Nagesh R. Sutar and Ketan P. Patil


Silica supported Co(ClO4)2 was prepared and found to be thermally stable over a long range of temperature. It was found to be an efficient, recyclable and heterogeneous catalyst for synthesis of both 5-unsubstituted 3, 4-dihydropyrimidinones and β-amino carbonyl compounds under solvent free condition. The simple procedure, high yield of desired products and solvent free reaction condition making it environment benign are important aspects of this protocol


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  • Universidade de Barcelona
  • ICMJE

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