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Ultrasound-promoted solvent- and catalyst-free benzoylation of amines at room temperature: A green procedure

Davood Habibi, Somayyeh Heydari, Alireza Faraji, Mahmoud Nasrollahzadeh


A greener improvement to the N-benzoylation of amines, phenols and alcohols by benzoyl chloride was achieved using ultrasound irradiation without any solvent and catalyst. This simple, fast and highly efficient green procedure provided the products in high purity and quantitative yield within minutes at room temperature. This protocol does not require any water quenches, solvent separations and purification steps such as column chromatography or recrystallization.


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  • Infraestrutura Nacional de Conhecimento da China (CNKI)
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  • Cosmos SE
  • Diretório de indexação de periódicos de pesquisa (DRJI)
  • Laboratórios secretos de mecanismos de pesquisa
  • Fator de impacto do artigo acadêmico (SAJI))
  • ICMJE

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